There are some live-USBs / live-CDs that do virus removal. There is a real advantage to this — they run outside of the infected system, so even if the system is rootkitted, or unable to boot, the live-USB will still work.
My hope is to find ones that are extremely easy to use, even for your grandma, so that we can give them to customers of FreeGeek and they can do the spyware-removal themselves.
|boot USB / CD||size||signatures updated|
on release ISO
|signatures can be updated|
|ease of use|
for your grandma
|Avira AntiVir — "Rescue System"||80mb||daily||easily updated via GUI|
|Dr.Web — "LiveDisk"||140mb||daily|
|Bit Defender — "Rescue CD"||320mb||every few months||automatically during boot|
|F-Secure — "Rescue CD"||120mb||every few years?||automatically during boot|